A method to increase the effectiveness of treatment for aggressive forms of cancer found in Cyprus

Scientists at the Cyprus Institute of Neurology and Genetics reported research results that could significantly improve the treatment of the most aggressive and therapy-resistant types of cancer. The findings were published in a peer-reviewed scientific journal.

The study focused on pancreatic and breast tumors, sarcomas, and melanomas — cancer types characterized by dense tissue structure and deformed blood vessels. These features often hinder chemotherapy from penetrating the tumor, reducing treatment effectiveness.

According to the institute, researchers used an approved antihistamine drug that helped soften the tumor structure and improve blood flow. Then, combined with standard chemotherapy, therapeutic ultrasound was applied to increase vessel permeability.

The combined approach weakened the tumor’s protective barrier, reduced tissue stiffness, and allowed drugs to reach cancer cells more effectively. As a result, a significant reduction in tumor size was recorded.

The institute notes that the obtained data opens new prospects in treating oncological diseases that previously responded poorly to existing therapy methods.